What We're Planning

The best way to find out what experiments we're planning is to read our grant proposals.

Here are links to our latest proposals. The first two are those we have just submitted to NIH and to CIHR (The Canadian Institutes for Health Research, the Canadian equivalent of NIH). These proposals aim to investigate transformation recombination (NIH) and the mechanisms of DNA uptake (CIHR). We are all currently working on prelimary data for these proposals.

Summary of recombination proposal

Complete recombination proposal

Summary of uptake proposal

Complete uptake proposal

The third proposal addresses the role of the Sxy transcriptional activator, considering both how the sxy gene is regulated and how the Sxy protein works with CRP to activate genes with CRP-S sites in their promoters. Its title is "Regulation of CRP-S promoters in H. influenzae and E. coli.".  This proposal was successfully funded in 2007. We are currently pursuing most of the goals outlined in this proposal.

Summary of Sxy proposal

Complete Sxy proposal


Here are links to two other successful previous proposals:

2001 CIHR proposal

1999 NIH proposal

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