Publications (Mizumoto lab members are underlined)


Kurashina M., Mizumoto K*.
Targeting endogenous proteins for spatial and temporal knock-down using auxin-inducible degron (AID) in Caenorhabditis elegans.
STAR Protocols  2023 Jan 13;4(1):102028. doi: 10.1016/j.xpro.2022.102028.

Mizumoto K*., Jin Y*., Bessereau JL*.
Synaptogenesis: unmasking molecular mechanisms using C. elegans.
Genetics 2023 Jan 11:iyac176. doi: 10.1093/genetics/iyac176.


Hendi A., Niu LG., Snow AW., Ikegami R., Wang ZW., Mizumoto K*.
Channel-independent function of UNC-9/Innexin in spatial arrangement of GABAergic synapses in C. elegans
eLIFE 2022;


Kurashina M., Wang J., Lin J., Lee KK., Johal A., Mizumoto K*.
Sustained expression of unc-4 homeobox gene and unc-37/Groucho in postmitotic neurons specifies the spatial organization of the cholinergic synapses in C. elegans
eLIFE 2021;10:e66011 DOI: 10.7554/eLife.66011


McDiarmid TA, Belmadani M, Liang J, Meili F, Mathews EA, Mullen GP, Hendi A, Wong WR, Rand JB, Mizumoto K, Haas K, Pavlidis P, Rankin CH.
Systematic phenomics analysis of autism-associated genes reveals parallel networks underlying reversible impairments in habituation.
Proc Natl Acad Sci U S A. 2020 Jan 7;117(1):656-667. doi: 10.1073/pnas.1912049116


Lu M., Mizumoto K*.
Gradient-independent Wnt signaling instructs asymmetric neurite pruning in C. elegans
eLIFE 2019;8:e50583 DOI: 10.7554/eLife.50583

Hendi A.#, Kurashina M.# and Mizumoto K. (# equal contribution)
Intrinsic and extrinsic mechanisms of synapse formation and specificity in C. elegans. (review)
Cellular and Molecular Life Sciences 2019 Jul;76(14):2719-2738


Hendi A. and Mizumoto K. (2018)
GFPnovo2, a brighter GFP variant for in vivo labeling in C. elegans.
microPublication Biology

McDiarmid TA, Au V, Loewen AD, Liang J, Mizumoto K, Moerman DG, Rankin CH.
CRISPR-Cas9 human gene replacement and phenomic characterization in Caenorhabditis elegans to understand the functional conservation of human genes and decipher variants of uncertain significance.
Dis Model Mech. 2018 Nov 26;11(12). pii: dmm036517. doi: 10.1242/dmm.036517.

Chen X., Shibata ACE.#,Hendi A.#,Kurashina M., Fortes E.,Weilinger NL., MacVicar B., Murakoshi H., Mizumoto K*. (# equal contribution)
Rap2 and TNIK control Plexin-dependent tiled synaptic innervation in C. elegans
eLIFE 2018;7:e38801 DOI: 10.7554/eLife.38801
BioRxiv 238352

Sugioka K., Fielmich LE., Mizumoto K., Bowerman B., van den Heuvel S., Kimura A., and Sawa H.
Tumor suppressor APC is an attenuator of spindle-pulling forces during C. elegans asymmetric cell division
PNAS 2018 doi: 10.1073/pnas.1712052115


Kratsios P, Kerk SY, Catela C, Liang J, Vidal B, Bayer EA, Feng W, De La Cruz ED, Croci L, Consalez GG, Mizumoto K, Hobert O.
An intersectional gene regulatory strategy defines subclass diversity of C. elegans motor neurons.
eLIFE 2017;6:e25751 DOI: 10.7554/eLife.25751


Miyazaki Y., Mizumoto K., Dey G., Kudo T., Chen LC., Meyer T. and Wandless TJ.
A novel method to rapidly create protein aggregates in living cells.
Nature communications 2016 7:11689.


Mizumoto K. and Shen K.
Two Wnts instruct topographic synaptic innervation in C. elegans.
Cell Reports 2013 5:389-396. PMID: 24139806

Mizumoto K. and Shen K.
Inter-axonal interaction defines tiled presynaptic innervation in C. elegans.
Neuron 2013 77(4):655-666. PMID: 23439119


Sugioka K., Mizumoto K. and Sawa H.
Wnt regulates spindle asymmetry to generate asymmetric nuclear beta-catenin in C. elegans.
Cell 2011 146(6): 942-954.

Yang XD., Huang S., Lo MC., Mizumoto K., Sawa H., Xu W., Robertson S., and Lin R.
Distinct and mutually inhibitory binding by two divergent beta-catenins coordinates TCF levels and activity in C. elegans.
Development 2011 138:4255-4265


Mizumoto K. and Sawa H.
Cortical beta-catenin and APC regulate asymmetric nuclear beta-catenin localization during asymmetric cell division in C. elegans.
Developmental Cell 2007 Feb; 12(2): 287 – 299

Mizumoto K. and Sawa H.
Two bs or not two bs, that is the question: regulation of asymmetric division by beta-catenin.
Trends in Cell Biology 2007 17(10): 465-473.


Goldstein B., Takeshita H., Mizumoto K. and Sawa H.
Wnt signals can function as positional cues in establishing cell polarity.
Developmental Cell 2006 Mar;10(3):391-396.