A
product of the UBC Cell Biology and Genetics undergraduate program,
I started my Masters Degree in the Roskams lab in January 2007.
My research focuses on interrupting epigenetic control of gene expression
during development in the postnatal mouse brain and examining how
this affects the proliferation and differentiation of neural stem
cells and progenitors. As a cell progresses from a neural stem cell
to a differentiated neuron or glia much of its progression is regulated
by the activation or silencing of specific genes that determine
cell identity. Histone deacetylases are a family of enzymes that
direct gene silencing during normal development; by inhibiting the
activity of specific groups of histone deacetylases in in vivo and
in vitro models of postnatal brain development I investigate the
role of these enzymes in proliferation and differentiation of neural
progenitors.
A
product of the UBC Cell Biology and Genetics undergraduate program,
I started my Masters Degree in the Roskams lab in January 2007.
My research focuses on interrupting epigenetic control of gene expression
during development in the postnatal mouse brain and examining how
this affects the proliferation and differentiation of neural stem
cells and progenitors. As a cell progresses from a neural stem cell
to a differentiated neuron or glia much of its progression is regulated
by the activation or silencing of specific genes that determine
cell identity. Histone deacetylases are a family of enzymes that
direct gene silencing during normal development; by inhibiting the
activity of specific groups of histone deacetylases in in vivo and
in vitro models of postnatal brain development I investigate the
role of these enzymes in proliferation and differentiation of neural
progenitors.